Open Journal Systems

Cover Image

Saliva: A mirror to health

Kavyashree Lokesh, Jayanthi K


Salivary composition enables it to fulfill multiple tasks, which is based both on components that originate in the oral, oropharyngeal mucosa and as secretions from the salivary glands themselves, as well as serum derivatives. Accordingly, salivary analysis facilitates the evaluation of both local and systemic changes in the body. Salivary analysis may also be used in order to examine specific disease-related alterations such as epithelial tumor markers, which is shown to be significantly increased in the saliva of oral squamous cell carcinoma. Similarly, patient’s salivary components are representative of its composition under physiological or pathological conditions, and these components that may be altered in several oral and systemic conditions, aid in the further understanding of the relationship between saliva and the disease pathogenesis, as well as its contribution to its diagnosis.


Antimicrobial; tumor marker; stimulated saliva; whole saliva

Full Text:



Lima DP, Diniz DG, Moimaz SA, Sumida DH, Okamoto AC. Saliva: Reflection of the body. Int J Infect Dis 2010;14:e184-8.

Lamster IB, Kaufman E. Diagnostic applications of saliva – A review. Crit Rev Oral Biol Med 2002;13:197-212.

Bailey B, Klein J, Koren G. Noninvasive methods for drug measurement in pediatrics. Pediatr Clin North Am 1997;44:15-26.

Meurman JH, Rantonen P, Pajukoski H, Sulkava R. Salivary albumin and other constituents and their relation to oral and general health in the elderly. Oral Surg Oral Med Oral Pathol 2002;94:432-7.

Greenberg MS, Glick M. Burket’s Oral Medicine Diagnosis and Treatment. 10th ed. India: Elsevier; 2003. p. 236-46.

Mandel ID. Salivary diagnosis: More than a lick and a promise. J Am Dent Assoc 1993;124:85-8.

Tabak LA. A revolution in biomedical assessment: The development of salivary diagnostics. J Dent Educ 2001;65:1135-9.


  • There are currently no refbacks.